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DeForest Lab Publications

DeForest Lab Cover Gallery

Selected Publications

  • Ruskowitz, E.R. & DeForest, C.A. Photoresponsive Biomaterials for Targeted Drug Delivery and 4D Cell Culture. Nature Reviews Materials, 3, 17087 (2018) DOI: 10.1038/natrevmats.2017.87. (link, pdf)
  • Badeau, B.A., Comerford, M.P., Arakawa, C.K., Shadish, J.A. & DeForest, C.A. Engineered Modular Biomaterial Logic Gates for Environmentally Triggered Therapeutic Delivery. Nature Chemistry, DOI: 10.1038/nchem.2917 (2018). (link, pdf)
  • Arakawa, C.K., Badeau, B.A., Zheng, Y. & DeForest, C.A. Multicellular Vascularized Engineered Tissues through User-Programmable Biomaterial Photodegradation. Advanced Materials, 29, 1703156 (2017). (link, pdf)
  • DeForest, C.A.* & Tirrell, D.A. A Photoreversible Protein-Patterning Approach for Guiding Stem Cell Fate in Three-Dimensional Gels. Nature Materials, 14, 523-531 (2015). (link, pdf) *Co-Corresponding Authorship
  • DeForest, C.A. & Anseth, K.S. Photoreversible Patterning of Biomolecules within Click-based Hydrogels. Angewandte Chemie International Edition, 51, 1816-1819 (2012). (link, pdf)
  • DeForest, C.A. & Anseth, K.S. Cytocompatible Click-based Hydrogels with Dynamically-Tunable Properties through Orthogonal Photoconjugation and Photocleavage Reactions. Nature Chemistry, 3, 925-931 (2011). (link, pdf)
  • DeForest, C.A., Polizzotti, B.D. & Anseth, K.S. Sequential Click Reactions for Synthesizing and Patterning 3D Cell Microenvironments. Nature Materials 8, 659-664 (2009). (link, pdf)
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    Full Publication List

  • Ruskowitz, E.R. & DeForest, C.A. Photoresponsive Biomaterials for Targeted Drug Delivery and 4D Cell Culture. Nature Reviews Materials, 3, 17087 (2018) DOI: 10.1038/natrevmats.2017.87. (link, pdf)
  • Photoresponsive Biomaterials for Targeted Drug Delivery and 4D Cell Culture
  • Badeau, B.A., Comerford, M.P., Arakawa, C.K., Shadish, J.A. & DeForest, C.A. Engineered Modular Biomaterial Logic Gates for Environmentally Triggered Therapeutic Delivery. Nature Chemistry, DOI: 10.1038/nchem.2917 (2018). (link, pdf)
  • Engineered Modular Biomaterial Logic Gates for Environmentally Triggered Therapeutic Delivery
  • Arakawa, C.K., Badeau, B.A., Zheng, Y. & DeForest, C.A. Multicellular Vascularized Engineered Tissues through User-Programmable Biomaterial Photodegradation. Advanced Materials, 29, 1703156 (2017). (link, pdf)
    *This article appears on the cover of the October 2017 issue of Advanced Materials and was featured in UW Medicine News.
  • Multicellular Vascularized Engineered Tissues through User-Programmable Biomaterial Photodegradation
  • Farahani, P.E., Adelmund, S.M., Shadish, J.A. & DeForest, C.A. Photomediated Oxime Ligation as a Bioorthogonal Tool for Spatiotemporally-Controlled Hydrogel Formation and Modification. Journal of Materials Chemistry B. 5, 4435-4442 (2017) (link, pdf)
    *This article was selected for the 2017 Emerging Investigator Award issue of the Journal of Materials Chemistry B, and appears on the cover of the June 2017 issue. More information is available here.
  • Photomediated Oxime Ligation as a Bioorthogonal Tool for Spatiotemporally-Controlled Hydrogel Formation and Modification
  • Arakawa, C.K. & DeForest, C.A. Designing Smart Biomaterials to Mimic & Control the Stem Cell Niche: Polymer Design and Development. Biology and Engineering of Stem Cell Niches, Elsevier. Oxford, UK. 295-314 (2017) (link)
  • Biology and Engineering of Stem Cell Niches
  • Swift, B.J., Shadish, J.A., DeForest, C.A. & Baneyx, F. Streamlined Synthesis and Assembly of a Hybrid Sensing Architecture with Solid Binding Proteins and Click Chemistry. Journal of the American Chemical Society, 139, 3958-3961 (2017) (link, pdf)
  • Streamlined Synthesis and Assembly of a Hybrid Sensing Architecture with Solid Binding Proteins and Click Chemistry
  • Uto, K. & DeForest, C.A. 時空間制御バイオマテリアルを用いた細胞力学記憶メカニズムの解明 Spatiotemporally Tunable Biomaterials for Revealing the Mechanism of Cellular Mechanical Memory (Article in Japanese). Journal of Japanese Biomaterials, 35, 36-41 (2017). (link, pdf)
  • Spatiotemporally Tunable Biomaterials for Revealing the Mechanism of Cellular Mechanical Memory
  • Uto, K., Aoyagi, T., DeForest, C.A., Hoffman, A.S. & Ebara, M. A Combinational Effect of “Bulk” and “Surface” Shape-Memory Transitions on the Regulation of Cell Alignment. Advanced Healthcare Materials, DOI: 10.1002/adhm.201601439 (2017). (link, pdf)
  • A Combinational Effect of “Bulk” and “Surface” Shape-Memory Transitions on the Regulation of Cell Alignment
  • Uto, K., Tsui, J.H., DeForest, C.A.* & Kim, D.H. Dynamically Tunable Cell Culture Platforms for Tissue Engineering and Mechanobiology. Progress in Polymer Science, 65, 53-82 (2016). (link, pdf) *Co-Corresponding Authorship
  • Dynamically Tunable Cell Culture Platforms for Tissue Engineering and Mechanobiology
  • Tibbitt, M.W., Shadish, J.A. & DeForest, C.A. Photopolymers for Multiphoton Lithography in Biomaterials and Hydrogels. Appears in Multiphoton Lithography: Techniques, Materials, and Applications, Wiley Publishing, 183-220 (2016). (link, pdf)
  • Photopolymers for Multiphoton Lithography in Biomaterials and Hydrogels
  • Urrios, A., Parra-Cabrera, C., Bhattacharjee, N., Gonzalez-Suarez, A.M., Rigat-Brugarolas, L.G., Nallapatti, U., Samitier, J., DeForest, C.A., Posas, F., Garcia-Cordero, J.L. & Folch, A. 3D-printing of transparent bio-microfluidic devices in PEG-DA. Lab on a Chip, 16, 2287-2294 (2016). (link, pdf)
  • 3D-printing of transparent bio-microfluidic devices in PEG-DA
  • Uto, K., DeForest, C.A. & Kim, D.H. Soft Shape-Memory Materials. Appears in Biomaterials Nanoarchitectonics, Elsevier Inc, 237-251 (2015). (link, pdf)
  • Soft Shape-Memory Materials
  • DeForest, C.A.* & Tirrell, D.A. A Photoreversible Protein-Patterning Approach for Guiding Stem Cell Fate in Three-Dimensional Gels. Nature Materials, 14, 523-531 (2015). (link, pdf) *Co-Corresponding Authorship
  • A Photoreversible Protein-Patterning Approach for Guiding Stem Cell Fate in Three-Dimensional Gels
  • Adzima, B.J., Kloxin, C.J., DeForest, C.A., Anseth, K.S. & Bowman, C.N. 3D Photofixation Lithography in Diels–Alder Networks. Macromolecular Rapid Communications, 33, 2092-2096 (2012). (link, pdf)
  • 3D Photofixation Lithography in Diels–Alder Networks
  • Kloxin, A.M., Lewis, K.J.R., DeForest, C.A., Seedorf, G.J., Tibbitt, M.W., Balasubramaniam, V & Anseth, K.S. Responsive Culture Platform to Examine the Influence of Microenvironmental Geometry on Cell Function in 3D. Integrative Biology, 4, 1540-1549 (2012). (link, pdf)
  • Responsive culture platform to examine the influence of microenvironmental geometry on cell function in 3D
  • DeForest, C.A. & Anseth, K.S. Advances in Bioactive Hydrogels to Probe and Direct Cell Fate. Annual Review of Chemical and Biomolecular Engineering, 3, 421-444 (2012). (link, pdf)
  • Bioactive Hydrogels for Regenerative Medicine
  • DeForest, C.A. & Anseth, K.S. Photoreversible Patterning of Biomolecules within Click-based Hydrogels. Angewandte Chemie International Edition, 51, 1816-1819 (2012). (link, pdf)
    *This article appears on the cover of the February 2012 issue of Angewandte and was selected as a “Very Important Paper” by the journal editors. It also was featured in Nature, Angewandte Chemie, and Lab on a Chip.
  • Photoreversible Patterning of Biomolecules within 3D Click Gels
  • DeForest, C.A. & Anseth, K.S. Cytocompatible Click-based Hydrogels with Dynamically-Tunable Properties through Orthogonal Photoconjugation and Photocleavage Reactions. Nature Chemistry, 3, 925-931 (2011). (link, pdf)
    *This article appears on the cover of the December 2011 issue of Nature Chemistry and has been highlighted in Chemistry World.
  • Cytocompatible Click-based Hydrogels with Dynamically-Tunable Properties through Orthogonal Photoconjugation and Photocleavage Reactions
  • Adzima, B.J., Tao, Y., Kloxin, C.J., DeForest, C.A., Anseth, K.S. & Bowman, C.N. Spatial and Temporal Control of the Alkyne–Azide Cycloaddition by Photoinitiated Cu(II) Reduction. Nature Chemistry, 3, 256-261 (2011). (link, pdf)
  • Spatial and Temporal Control of the Alkyne–Azide Cycloaddition by Photoinitiated Cu(II) Reduction
  • Sims, E.A., DeForest, C.A. & Anseth, K.S. A Mild, Large-Scale Synthesis of 1,3-Cyclooctanedione: Expanding Access to Difluorinated Cyclooctyne for Copper-Free Click Chemistry. Tetrahedron Letters, 52, 1871-1873 (2011). (link, pdf)
    *This article was featured by Vertical News
  • A Mild, Large-Scale Synthesis of 1,3-Cyclooctanedione: Expanding Access to Difluorinated Cyclooctyne for Copper-Free Click Chemistry
  • DeForest, C.A., Sims, E.A. & Anseth, K.S. Peptide-Functionalized Click Hydrogels with Independently Tunable Mechanics and Chemical Functionality for 3D Cell Culture. Chemistry of Materials, 22, 4783-90 (2010). (link, pdf)
  • Peptide-Functionalized Click Hydrogels with Independently Tunable Mechanics and Chemical Functionality for 3D Cell Culture
  • Johnson, L.M., DeForest, C.A., Pendurti, A., Anseth, K.S. & Bowman, C.N. Formation of Three-Dimensional Hydrogel Multilayers Using Enzyme-Mediated Redox Chain Initiation. ACS Applied Material Interfaces, 2, 1963-1972 (2010). (link, pdf)
  • Formation of Three-Dimensional Hydrogel Multilayers Using Enzyme-Mediated Redox Chain Initiation
  • Lawson, M.C., Hoth, K.B., DeForest, C.A., Bowman, C.N. & Anseth, K.S. Inhibition of Staphylococcus epidermidis Biofilms using Polymerizable Vancomycin Derivatives. Clin Orthop Relat Res, 468, 2081-2091 (2010). (link, pdf)
  • Inhibition of Staphylococcus epidermidis Biofilms using Polymerizable Vancomycin Derivatives
  • DeForest, C.A., Polizzotti, B.D. & Anseth, K.S. Sequential Click Reactions for Synthesizing and Patterning 3D Cell Microenvironments. Nature Materials, 8, 659-664 (2009). (link, pdf)
    *This article has been highlighted in Nature, Chemistry World, F1000, as well as others
  • Sequential Click Reactions for Synthesizing and Patterning 3D Cell Microenvironments
  • Benton, J.A., DeForest, C.A., Vivekanandan, V. & Anseth, K.S. Photocrosslinking of Gelatin Macromers to Synthesize Porous Hydrogels that Promote Valvular Interstitial Cell Function. Tissue Engineering Part A, 15 3221-3230 (2009). (link, pdf)
  • Tunable Microporous Photocrosslinking of Gelatin Macromers to Synthesize Porous Hydrogels that Promote Valvular Interstitial Cell Function  

    Cover Gallery

  • Advanced Materials 2017 Vol 29 Issue 37 (pdf)
  • Farahani 2017 JMCb Cover
  • Chemical Engineering Progress August 2017 (pdf)
  • DeForest 2017 CEP Cover
  • Journal of Materials Chemistry B 2017 Issue 23 (pdf)
  • Farahani 2017 JMCb Cover
  • Angewandte Chemie International Edition 2012 Vol 51 Issue 8 (pdf)
  • DeForest Angewandte Chemie 2012 Cover
  • Nature Chemistry 2011 Vol 3 Issue 12 (pdf)
  • DeForest Nature Chemistry 2011 Cover

    Research Highlights

  • DeForest, C.A., Zhang, H., Memic, A., Dokmeci, M.R. & Khademhosseini, A. Research Highlights. Lab on a Chip 12, 3540-3542 (2012). (link, pdf)
  • Selimović, Š., DeForest, C.A., Dokmeci, M.R. & Khademhosseini, A. Research Highlights. Lab on a Chip 12, 2995-2997 (2012). (link, pdf)
  • Selimović, Š., DeForest, C.A., Dokmeci, M.R. & Khademhosseini, A. Research Highlights. Lab on a Chip 12, 2289-2291 (2012). (link, pdf)
  • Selimović, Š., DeForest, C.A., Dokmeci, M.R. & Khademhosseini, A. Research Highlights. Lab on a Chip 12, 2094-2096 (2012). (link, pdf)
  • Selimović, Š., DeForest, C.A., Dokmeci, M.R. & Khademhosseini, A. Research Highlights. Lab on a Chip 12, 2015-2017 (2012). (link, pdf)
  • Selimović, Š., DeForest, C.A., Dokmeci, M.R. & Khademhosseini, A. Research Highlights. Lab on a Chip 12, 1739-1741 (2012). (link, pdf)
  • Google Scholar

    An up-to-date list of publications can be found through the group's Google Scholar page:

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